I thought about this before and came up with these options:
1. Use Bronco type set up with Dana 50 ttb (Coils, Shocks, Trailing Arms). This is not a coil over. Actually pretty straight forward but may need special coils due to different weights of the 351 vs 6.9/7.3.
2. Coil over with Dana 60 and some type of link bar set up (triangulated or otherwise). Requires math I don't have, or a program from Pirate 4x4. Not really worth the effort unless hardcore wheeling. If set up for rock crawling, they make the body sway like no other on the street (i.e. not the best for the street, and who hardcore wheels a F250/350 long bed?!?!).
3. Superduty set up with solid axle Dana 50, or Dana 60 depending on the year. Requires leaf springs but custom hangers because spring perches on the Dana 50/60 are cast into the housing and are narrower than current width of the F250/350 stock hangers. Would be easiest with a parts truck.
If I were to have done it, I would do #1 since I have a D50 and not a D60. However, I replaced every D50 bushings with poly and put new leaf springs on (along with bushings) as part of a lift and I am darn happy with it. A D50 does have better street manners than a sold axle, D60 or otherwise. It was a cee you next tuesday to wrestle the D50 solo, but outside replacing the bushings I really don't mind that axle despite it's reputation. It's going to hold up to 99% of what folks are going to do with this truck. Now, give me a free D60 and all the swap over parts and I'd light my D50 on fire.
But let's be honest, it took me one weekend to replace all D50 bushings, including the leaf springs, which happened once in the truck's 30+ year life time. I think we're both going to survive. With new steering components and an alignment and my tires look perfect after 50k miles.