From my experience, YES! 7.3's have issues with the valve guides, not the valves themselves. It seemed to usually happen from 120,00 to 150,000 miles. Some earlier, some later. I've seem a couple that had been driver too far and had been grenaded from a dropped/broken valve. I've also seen a '92 or '93 factory turbo 7.3 that had 305,000 miles on it before it happened. It seems like good maintenance helps, but they all seem to do it after a while. Our solution was to have our machine shop install bronze valve guides. Even if you have a "full valve job", it will still happen with the harder guides. 6.9's didn't seem to suffer from this issue and it's only the exhaust valves. You will hear a chuffing or popping noise in the exhaust. Anything from the intake is not the same problem. Problem: turbos tend to muffle this noise. You can check by removing the valve covers and looking at the insides of them. There will be a residue on the valve covers that isn't from oil. It will look "carbony". This is because as the guide wears and the valve leans to the side, exhaust gasses will slip by the valve and probably burn a little bit of oil. Since the cylinder has so much pressure at this time, the residue will collect on the bottom of the valve cover as well as on the spring, rocker arm, and valve.