So far I've run out 3 tanks of WMO commuting. (140 mile round trip)
So far, the differences I've noticed are minimal. Running a 50/50 mix, engine seems a little quieter, power is down just a tad, morning starts are actually quicker, EGTs run about 75* hotter at cruising speed. The exhaust smokes a little more under acceleration and smells a little worse. Enough so that yesterday a friend (a lifetime diesel mechanic who didn't know I was running WMO) walked by the truck, paused, then stuck his head under the truck to smell the exhaust. Came out telling me that I had better sell the truck because he thinks it's starting to burn some oil.
I have had to haul one car on the trailer, I switched tanks from the WMO tank to the diesel while under a load. Once all the WMO was out of the system I could notice a considerable difference in power. In the future, I will be running straight diesel if pulling anything over 6000#. If the roads around here were straight or relatively flat it may be different. But around here there are hills everywhere.
The filtering rig that I built is also air powered and portable. 30 gallon capacity, takes about 30 minutes start to finish to process 30 gallons. All in all, I'm glad I built the filtering rig and can run the WMO in the truck.