I do, but it is in my 6.0, and my old VW.... The 6.0 shears the oil horribly. Even with a quality synthetic (I have been running Chevron DELO Full Synthetic in the "silver" jug), and I still change it at ~5000 miles. However, I do see the benefits of a synthetic in this truck, as it cold starts much easier, and sitction is almost non-existent on 143,000+ mile injectors. But just like with conventional 15W-40 (I had been using the Motorcraft "Powerstroke" Oil because it was 5 quarts instead of 4) and toward the 5000 mile mark, I can feel a difference especially when the engine is cold (both in the operation definition, and physical temperature). I can feel a bit of stiction with both oils, the conventional being worse, approaching 5000 miles. Change the oil, and withing a day, it is completely gone. The biggest thing I have found living here in the north the advantage of synthetic is cold starting. Last year I still had the Motorcraft 15W-40 in the truck and it was bouncing around 0F, and had been several degrees below 0 overnight. That morning the truck would not start because of the molasses in the crankcase. An hour on the block heater and it started right up. This year, same conditions but running the Delo Synthetic, it will fire right up without the block heater. I normally keep it plugged in, but that is just a preference for me...... Even with synthetic and a bypass on my 6.0 I would not benefit from extended OCI's because the 6.0 actually "damages" the oil with the shuttle valves in the injectors. It quite literally cuts the oil. There have been many tests showing that conventional and synthetic oil have been "thinned" over the course of 5000 miles just by the searing of the oil. What has been found is if an XXW-40 is installed, by then 5000 mile mark it has thinned to be the equivalent of a XXW-30 oil, just by normal operation of the engine. So for me, the synthetic is to keep the injectors happy, and ease of cold startup. I use the same oil in the Jetta because I have it on-hand, and a just over 4 quarts..... conventional or synthetic isn't all that expansive of and oil change. But I will say, the Jetta does operate quieter (mechanically) with the synthetic than it did with a conventional. Don't get me wrong, it is a loud obnoxious little diesel (It is actually louder running than the 6.0, my family can hear me pull up in the Jetta, they can't in the truck....

).... but you hear the valvetrain much less with the synthetic.
This is my opinion, and not supported by any testing or numbers. But I have owned the 6.0 long enough to be able to tell by sound and performance, the synthetic makes it much happier. I also use ONLY the Motorcraft filters for it (Oil and Fuel) which are made by RACOR. There may be better filters out there, but there are definitely much WORSE filters, so I stick with what works for me.