Drove truck last evening to car wash (3 miles each direction) to clean dirt from weekend and didn't really notice any vibration until the return trip back home, curious if heat buildup has something to do with it??? Pulled into garage and checked driveshafts, both seem tight (no slop in u-joints), center support seems tight as well, nothing felt hot or even warm. Re-checked alignment of u-joints by laying a long straight edge from joint to joint and they are correct, not even one tooth off..... Rear is full, trans is full, transfer case is full, joints all have grease in them. To offer a better description of this issue, when I first noticed it at highway speed, I immediately thought the front hubs were locked which they were not. Then realized the vibration was only noticeable when pressing on throttle. Later I was on dirt road driving very slow (less than 5mph) and I could hear what I thought was the squeak, squeak, squeak of a dry u-joint. This noise only occurred when the engine was holding back the weight of the truck (no foot on gas pedal) going down hill. Press on gas pedal and squeak goes away. I pointed the truck north and headed for home. During the 110 mile return trip it had the same vibration symptoms at highway speed which I only noticed when pressing gas pedal. I'm stumped, and currently considering one piece driveshaft however initial indications say it may be too long (my measurement is 78") and price estimate of nearly $700.00 makes other avenues more appealing. Noticed "Timken" offers a center support??? Also wondering about the grease I used to pack the MOOG if that created the issue? I simply used grease from my grease gun which I use on everything from truck to tractor, it's valvoline grease. Also curious if the center support bearing needs to be "shimmed" or lowered. Remember this truck was born an F250 and I installed F350 rear blocks so the driveshaft has steeper angle than F250? Maybe F350 has factory shim or possibly different center support than F250? I'm rambling and now closing my piehole...