Synthetics are good in anything, just depends on the maintenance. I've run Amsoil products for a very long time, and converted one PSD over at over 180k on the miles. If an engine has some type of sealing issue (piston, piston rings, valveguide and seals, whatever), there is a potential for oil consumption to go up and leaks to happen. Check out Auto Rx and do a couple of clean and rinse cycles if you decide to go synthetic with an engine that has a lot of miles on it.