The 300 was put into pretty much everything, after 92 or so it was a delete option in F350's, but, was available until 96, 97 was 351/460 or diesel only.
I have seen it in F600's and 700's clean through from 65 until the mid 80's. A 300 might not be a powerhouse, but, with the right gearing they WILL get the job done. With advertised torque peaks from 1200-2400 rpm with no changes to the engine, you have to realize that it acts very much like an I-6 diesel, being a high torque low rpm engine.
Looking at the '81 engine spec chard from the Ford brochure, you can see why they were popular in work trucks of that era:
You must be registered for see images
Torque on par with the 351 of the day, and only really outdone by the 400.
They are extremely common in airport ground equipment, personally the biggest piece of equipment I have worked on that had one is one of our aircraft tugs, 23,000 lbs working weight, 175,000lb tow capacity.
It was in production right up until 2000 for industrial apps, still with a 1bbl on it.