How is dumping the muffler going to help? There are a whole lot of factors that contribute to drone so each truck is different and we can't really write foolproof prescriptions for other people's trucks unless they pretty much match in the setup. In my experience, removing the muffler doesn't do that. Interestingly, when I changed my timing (well Mel did it but...) from 7.5 to 9.5, the drone lessened a LOT. Compression ratio changes and cam timing can also add or detract from a drone. Pipe size is one major contributor to a drone (the velocity and sound frequencies of the gasses in the pipe) and also pipe wall thickness. Cheap, thinwall pipe has more droning tendencies. Often, turbos help with drone too because they "chop up" the exhaust pulses. I spent a few days a Borla in the mid-'90s and watched how they prototype a system. They have to do a LOT of sound tuning and matching of characteristics (pipe size with muffler type, etc) to make a system that won't be objectionable. People are a lot more forgiving of noise when they corncob a cheap system for themselves versus when they pay $600 for a system.
What I know... with the original Banks 3-inch system... no drone on my truck. Even with the corncob 3-inch system I had to have installed during a road trip after the Banks system finally rotted off (after only 16 years, can you believe it!) ... no drone. 4-inch system... drone at 1800 rpm. I want to go back to no drone and a nice quiet truck. The difference in power between 3 and 4 (or 5)... negligible, if it exists at all. Sometimes you can go too big and move the torque band higher than you want. Some time back, I posted the flow rates of the different size pipes and the hot exhaust flow of a 6.9 & 7.3 engines. A 3-inch system is MORE than enough to make maximum power in a turbocharged IDI in most rigs. There are a few highly built IDIs that might need more but IIRC, a 3.5 inch system can flow as much as 400 hp needs and how many of us are making 400... or 300... or even 250 for that matter. Bigger beyond what's needed doesn't equate to more power so why spend more money than you need to make your max power AND then possibly suffer with a drone or noise you don't like. You can always put a 5-inch tip on it if it's that look you like.