I changed out my injectors as part of the same job when I changed the IP. I didn't have to consider this aspect.
That being said, if the IP is in place, and the hard lines are in place, then the answer is, probably yes. You certainly want to avoid crimping one of those hard lines. IF you're replacing all 8 injectors, it might almost be worth your time and effort to just remove the IP with all hard lines attached. If you do that, be sure to review Mel's article about the fuel delivery system. It's in the Tech section, 2nd page I believe.
If you leave the IP in place there are two obstacles to loosening the lines at the IP. 1) The hard lines coming in toward the bottom of the IP are hard to do. You almost need a special tool. It's sort of like an open sided long socket. 2) Each side, each set of four hard lines, has clamps attaching them to each other. These are easy enough to remove, but be absolutely sure to replace them. Otherwise those hard line will self-destruct.
That's my thoughts on the subject. Personally, I'd remove the IP with lines attached if I were doing all injectors. You should time the engine with new injectors anyway, so it's not that big a deal.